A propósito de un caso: colitis isquémica relación con clozapina / No disponible

No disponible

Cognición social en pacientes con esquizofrenia, familiares de primer grado y controles sanos. Comparación entre grupos y análisis de variables clínicas y sociodemográficas relacionadas / Social cognition in patients with schizophrenia, their unaffected first degree relatives and healthy controls. Comparison between groups and analysis of associated clinical and sociodemographic variables

Objetivo: Evaluar y comparar la cognición social en pacientes con esquizofrenia, familiares de primer grado y controles sanos. Estudiar la relación que guarda la cognición social con la cognición no social, la psicopatología y otras variables clínicas y sociodemográficas. Método: La muestra total la formaron pacientes diagnosticados de esquizofrenia paranoide (n = 29), familiares sanos de primer grado (n = 21) y controles (n = 28). Todos los grupos fueron evaluados con un cuestionario ad hoc y la Escala de Cognición Social que evalúa los dominios: procesamiento emocional, percepción social y estilo atribucional en la población española. El grupo de pacientes fue evaluado también con la Escala para el Síndrome Positivo y Negativo de la Esquizofrenia y el Mini-Examen Cognoscitivo. Los datos fueron analizados con el paquete estadístico SPSS versión 15.0. Resultados: Los pacientes puntuaron significativamente peor en todos los dominios de la cognición social evaluados en comparación con los controles y en el dominio estilo atribucional en comparación con los familiares. El tipo de psicopatología correlacionó de forma negativa y estadísticamente significativa con dominios diferentes de la cognición social: la sintomatología negativa con el procesamiento emocional y el estilo atribucional y la sintomatología positiva con la percepción social. Las puntuaciones en la cognición básica correlacionaron de forma positiva y estadísticamente significativa con los dominios percepción social y estilo atribucional. Conclusión: La cognición social se ha convertido en un interesante objeto de estudio, especialmente por la relación que guarda con la cognición no social, la psicopatología y el funcionamiento global de los pacientes, aportando nuevos elementos a considerar en la detección precoz, el tratamiento integral y la rehabilitación psicosocial de los pacientes. Su conceptualización como variable de rasgo y la consideración de la existencia de un continuum entre pacientes y familiares son hipótesis plausibles que requieren mayor investigación (AU)

Aim: To evaluate and compare the social cognition in patients with schizophrenia, healthy first-degree relatives and controls, by studying the relationship between social cognition and nonsocial cognition, psychopathology, and other clinical and sociodemographic variables. Method: The total sample was comprised of patients diagnosed with paranoid schizophrenia (N = 29), healthy first-degree relatives (N = 21) and controls (N = 28). All groups were assessed with an ad hoc questionnaire and a Social Cognition Scale, which assessed the domains: emotional processing, social perception and attributional style in a Spanish population. The patient group was also assessed with the Scale for the Positive and Negative Syndrome Scale and the Minimental state examination. Statistical analyses were performed with SPSS version 15.0. Results: Patients scored significantly worse in all domains of social cognition assessed, compared with controls, and mastery attributional style, compared with relatives. The type of psychopathology correlated negatively and statistically significantly with different domains of social cognition: negative symptoms with emotional processing and attributional style, and positive symptoms with social perception. Basic cognition scores correlated positively and statistically significantly with the domains social perception and attributional style. Conclusion: Social cognition has become an interesting object of study, especially in how it relates to non-social cognition, psychopathology and global functioning of patients, bringing new elements to be considered in the early detection, comprehensive treatment and psychosocial rehabilitation of patients. Its conceptualization as trait variable, the consideration of the existence of a continuum between patients and relatives are plausible hypotheses that require further research(AU)

Social cognition in patients with schizophrenia, their unaffected first degree relatives and healthy controls. Comparison between groups and analysis of associated clinical and sociodemographic variables.

AIM: To evaluate and compare the social cognition in patients with schizophrenia, healthy first-degree relatives and controls, by studying the relationship between social cognition and nonsocial cognition, psychopathology, and other clinical and sociodemographic variables. METHOD: The total sample was comprised of patients diagnosed with paranoid schizophrenia (N = 29), healthy first-degree relatives (N = 21) and controls (N = 28). All groups were assessed with an ad hoc questionnaire and a Social Cognition Scale, which assessed the domains: emotional processing, social perception and attributional style in a Spanish population. The patient group was also assessed with the Scale for the Positive and Negative Syndrome Scale and the Mini-mental state examination. Statistical analyses were performed with SPSS version 15.0. RESULTS: Patients scored significantly worse in all domains of social cognition assessed, compared with controls, and mastery attributional style, compared with relatives. The type of psychopathology correlated negatively and statistically significantly with different domains of social cognition: negative symptoms with emotional processing and attributional style, and positive symptoms with social perception. Basic cognition scores correlated positively and statistically significantly with the domains social perception and attributional style. CONCLUSION: Social cognition has become an interesting object of study, especially in how it relates to non-social cognition, psychopathology and global functioning of patients, bringing new elements to be considered in the early detection, comprehensive treatment and psychosocial rehabilitation of patients. Its conceptualization as trait variable, the consideration of the existence of a continuum between patients and relatives are plausible hypotheses that require further research.